SCHEMBL21790483

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21790482	1.00	OPRK1 (0.44)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	Hydrochloric Acid SCHEMBL11007729	0.85	POLB (0.42)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL14469645	0.85	OPRK1 (0.47)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL28170722	0.79	POLB (0.45)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL21799494	0.77	TAAR1 (0.40)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL2622208	0.76	CHRM2 (0.59)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL8260622	0.76	CHRM2 (0.59)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL2622209	0.76	CHRM2 (0.59)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL19616773	0.75	CYP3A4 (0.47)	OPRK1CHRM2CHRM1ADRA1ASLC6A3
	SCHEMBL27835925	0.75	AR (0.39)	OPRK1CHRM2CHRM1ADRA1ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.