Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23456093 | 0.85 | NPC1 (0.44) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL31299182 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL12403813 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL25766068 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL21790728 | 0.77 | ESR1 (0.48) | ALDH1A1MAPK1HSD17B10L3MBTL1NR1H4 | |
| SCHEMBL10457306 | 0.77 | MAPT (0.34) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL13091135 | 0.74 | GAA (0.45) | SMN1; SMN2ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL2125769 | 0.73 | TP53 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21790575 | 0.73 | MEN1 (0.53) | SMN1; SMN2NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL23084860 | 0.73 | KDM4E (0.38) | SMN1; SMN2ALDH1A1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | SMN1; SMN2 3208/4885ALDH1A1 1049/4885MAPK1 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.