Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179098 | 1.00 | GCK (0.56) | GCKNQO2MAOBNFE2L2 | |
| SCHEMBL2177154 | 0.90 | GCK (0.52) | GCKNQO2 | |
| SCHEMBL2177146 | 0.90 | GCK (0.52) | GCKNQO2 | |
| SCHEMBL2176737 | 0.80 | GCK (0.64) | GCK | |
| SCHEMBL2176744 | 0.80 | GCK (0.64) | GCK | |
| SCHEMBL3605126 | 0.76 | PLA2G2A (0.40) | GCK | |
| SCHEMBL17060024 | 0.73 | PLA2G2A (0.46) | — | |
| SCHEMBL2176171 | 0.72 | GCK (0.73) | GCK | |
| SCHEMBL1427178 | 0.71 | MEN1 (0.64) | GCKMAOB | |
| SCHEMBL2177456 | 0.70 | GCK (0.73) | GCKNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178765-A1 | NOVEL GLUCOKINASE ACTIVATORS AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2012-07-12 | — | — | US | disclosed |
| WO-2011081280-A2 | NOVEL GLUCOKINASE ACTIVATORS AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178765-A1 | NOVEL GLUCOKINASE ACTIVATORS AND PROCESSES FOR THE PREPARATION THEREOF | GCK, GCKR, HK1 | GCK 1/4885NQO2 1803/4885MAOB 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.