Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118703 | 0.84 | TSHR (0.41) | SLC6A4TACR1SLC6A3SLC6A2 | |
| SCHEMBL2180201 | 0.82 | HTR2A (0.38) | SLC6A4TACR1SLC6A3SLC6A2 | |
| SCHEMBL2179928 | 0.82 | SLC6A4 (0.38) | SLC6A4TACR1SLC6A3SLC6A2HTR2C | |
| SCHEMBL28775360 | 0.80 | HTR2A (0.53) | SLC6A4TACR1SLC6A2HTR2COPRL1 | |
| SCHEMBL8086617 | 0.79 | OPRL1 (0.50) | KDM1ASLC6A4TACR1MAPTOPRL1 | |
| SCHEMBL2180437 | 0.78 | SLC6A4 (0.41) | SLC6A4TACR1SLC6A3SLC6A2 | |
| SCHEMBL5728531 | 0.75 | TACR1 (0.49) | KDM1ASLC6A4TACR1SLC6A3SLC6A2 | |
| SCHEMBL31322451 | 0.75 | OPRL1 (0.56) | KDM1ATACR1MAPTOPRL1 | |
| SCHEMBL5728524 | 0.75 | TACR1 (0.49) | KDM1ASLC6A4TACR1SLC6A3SLC6A2 | |
| SCHEMBL186127 | 0.75 | OPRL1 (0.56) | KDM1ATACR1MAPTOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844299-B | Desinsection aryl-pyrrolidine alkane | BAYER CROPSCIENCE AG (DE) | 2016-03-30 | — | — | CN | disclosed |
| EP-2519499-B1 | PESTICIDAL ARYLPYRROLIDINES | BAYER IP GMBH (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-8536201-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-17 | — | — | US | disclosed |
| CN-102844299-A | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-12-26 | — | — | CN | disclosed |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | DDT, CYP4X1, CHRM2 | KDM1A 1270/4885SLC6A4 2061/4885TACR1 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.