Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.41 |
| ▸ | TACR1 | P25103 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844322 | 0.89 | SLC6A4 (0.33) | SLC6A4TACR1KCNH2SLC6A2SLC6A3 | |
| SCHEMBL118703 | 0.89 | TSHR (0.41) | SLC6A4TACR1KCNH2SLC6A2SLC6A3 | |
| SCHEMBL14844401 | 0.89 | SLC6A4 (0.33) | SLC6A4TACR1KCNH2SLC6A2SLC6A3 | |
| SCHEMBL115415 | 0.89 | SLC6A4 (0.33) | SLC6A4TACR1KCNH2SLC6A2SLC6A3 | |
| SCHEMBL901681 | 0.82 | OPRM1 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18229253 | 0.81 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL115890 | 0.81 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL28205007 | 0.81 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL794941 | 0.80 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL2180925 | 0.78 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3CYP2D6NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519499-B1 | PESTICIDAL ARYLPYRROLIDINES | BAYER IP GMBH (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-8536201-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-17 | — | — | US | disclosed |
| CN-102844299-A | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-12-26 | — | — | CN | disclosed |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | DDT, CYP4X1, CHRM2 | SLC6A4 2061/4885TACR1 473/4885KCNH2 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.