Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21794019 | 0.86 | SCN8A (0.70) | SCN8ASCN1A | |
| SCHEMBL30845676 | 0.82 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL21772976 | 0.82 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL21772975 | 0.82 | SCN8A (1.00) | SCN8ASCN1A | |
| SCHEMBL21794020 | 0.82 | SCN1A (0.70) | SCN8ASCN1A | |
| Hydrogen Sulfide SCHEMBL21794074 | 0.80 | SCN8A (0.64) | SCN8ASCN1A | |
| SCHEMBL21793974 | 0.80 | SCN8A (0.69) | SCN8ASCN1A | |
| SCHEMBL21793986 | 0.77 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL21794022 | 0.76 | SCN8A (0.52) | SCN8ASCN1A | |
| SCHEMBL19634151 | 0.72 | SCN8A (0.70) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047312-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |