Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21794497 | 1.00 | PPID (0.65) | PPIDL3MBTL1HTTCASP1KLKB1 | |
| Hydrochloric Acid SCHEMBL30638083 | 0.99 | PPID (0.64) | PPIDL3MBTL1HTTCASP1KLKB1 | |
| Hydrochloric Acid SCHEMBL23699687 | 0.87 | PPID (0.47) | PPIDALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL23699686 | 0.87 | PPID (0.47) | PPIDALDH1A1NPSR1 | |
| SCHEMBL21794720 | 0.85 | FNTA (0.49) | PPIDL3MBTL1ALDH1A1 | |
| SCHEMBL23712605 | 0.85 | FNTA (0.49) | PPIDL3MBTL1ALDH1A1 | |
| SCHEMBL2039871 | 0.79 | PPID (1.00) | PPIDL3MBTL1HTTCASP1DRD1 | |
| SCHEMBL4816369 | 0.75 | PPID (0.63) | PPIDL3MBTL1ALDH1A1NPSR1TAS1R3 | |
| SCHEMBL23699693 | 0.73 | FNTA (0.61) | ALDH1A1NPSR1 | |
| SCHEMBL23699692 | 0.73 | FNTA (0.61) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043831-A1 | COMPOUNDS FOR THE MODULATION OF CYCLOPHILINS FUNCTION | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-03-05 | — | — | WO | disclosed |