Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23712605 | 1.00 | FNTA (0.49) | FNTAFNTBPPIDALDH1A1MAPT | |
| SCHEMBL23699693 | 0.89 | FNTA (0.61) | FNTAFNTBALDH1A1CRHBPCRHR2 | |
| SCHEMBL23699692 | 0.89 | FNTA (0.61) | FNTAFNTBALDH1A1CRHBPCRHR2 | |
| SCHEMBL21794498 | 0.85 | PPID (0.65) | PPIDALDH1A1L3MBTL1 | |
| SCHEMBL21794497 | 0.85 | PPID (0.65) | PPIDALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30638083 | 0.85 | PPID (0.64) | PPIDALDH1A1L3MBTL1 | |
| SCHEMBL21776958 | 0.84 | FNTA (0.48) | FNTAFNTBALDH1A1CRHBPCRHR2 | |
| SCHEMBL21776957 | 0.84 | FNTA (0.48) | FNTAFNTBALDH1A1CRHBPCRHR2 | |
| SCHEMBL21794878 | 0.75 | LMNA (0.49) | ALDH1A1MAPTCRHBPCRHR2MMP1 | |
| SCHEMBL4421021 | 0.73 | ALDH1A1 (0.49) | FNTAFNTBPPIDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043831-A1 | COMPOUNDS FOR THE MODULATION OF CYCLOPHILINS FUNCTION | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-03-05 | — | — | WO | disclosed |