⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12216595 | 1.00 | — | — | |
| SCHEMBL7136561 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL21114287 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL11258783 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL1302104 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL21114300 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL21114234 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL21114321 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL12216593 | 0.97 | ADH1A (0.41) | — | |
| SCHEMBL96256 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918056-A | ANTITUMOR AGENTS | HEALTH RESEARCH, INC. (ROSWELL PARK DIVISION) (US) | 1990-04-17 | — | — | US | claimed |
| US-4321366-A | Process of preparing 2-azido-2-deoxyarabinofuranosyl halides | RESEARCH CORPORATION (US) | 1982-03-23 | — | — | US | claimed |
| US-4230698-A | ANTITUMOR AGENTS, VIRICIDES, AND MICROBIOCIDES | RESEARCH CORPORATION (US) | 1980-10-28 | — | — | US | claimed |
| EP-1470173-B1 | TWO-CONSTITUENT POLYURETHANE COMPOSITION HAVING HIGH EARLY STRENGTH | SIKA TECH AG (CH) | 2017-03-01 | — | — | EP | disclosed |
| CN-105143217-A | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions | CAYMAN CHEMICAL CO INC | 2015-12-09 | — | — | CN | disclosed |
| CN-104583201-A | Difluorolactam compounds as EP4 receptor selective agonists for use in the treatment of EP4 mediated diseases and conditions | CAYMAN CHEMICAL CO INC | 2015-04-29 | — | — | CN | disclosed |
| CN-101952275-B | Modulators for amyloid protein beta | HOFFMANN LA ROCHE | 2014-06-18 | — | — | CN | disclosed |
| CN-101743246-B | 2-oxo-2- (2-phenyl-5,6,7,8-tetrahydro-indolizin-3-yl) -acetamide derivatives and related compounds as antifungal agents | F2G LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-102762560-A | Disubstituted heteroaryl-fused pyridines | NOVARTIS AG | 2012-10-31 | — | — | CN | disclosed |
| US-8039641-B2 | Tetrahydrofuro[3,2-b] pyrrol-3-one intermediates | AMURA THERAPEUTICS LIMITED (GB) | 2011-10-18 | — | — | US | disclosed |
| US-20110166191-A1 | 3-(2-amino-ethyl)-5-(3-cyclohexyl-propylidene)-thiazolidine-2,4-dione and its derivatives as multiple signaling pathway inhibitors and for the treatment of cancer | ZHANG SHIJUN | 2011-07-07 | — | — | US | disclosed |
| US-4133959-A | Aryloxyalkyl diketones | STERLING DRUG INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4046801-A | 13-Cis prostaglandin derivatives | SYNTEX (U.S.A.) INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-4039669-A | DERMATOLOGICAL CONDITIONS, ACNE, STEROIDS | STERLING DRUG INC. (US) | 1977-08-02 | — | — | US | disclosed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3992437-A | Polyhydrophenanthrene derivatives | STERLING DRUG INC. (US) | 1976-11-16 | — | — | US | disclosed |
| US-3982010-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3941781-A | Preparation of 3-alkylthiomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3932482-A | CARDIOTONIC | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |