SCHEMBL217947

SCHEMBL217947

C[C]1C=Cc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
ACHE P22303 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 2/20 0.46
IDO1 P14902 2/20 0.46
KDM4E B2RXH2 1/20 0.46
BCHE P06276 1/20 0.46
POLB P06746 1/20 0.46
PTPRC P08575 1/20 0.46
THRB P10828 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
PTPN1 P18031 1/20 0.46
CES1 P23141 1/20 0.46
RECQL P46063 1/20 0.46
PTPN22 Q9Y2R2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27948214 0.97 LMNA (0.44) LMNAMEN1KMT2AMAPTACHE
SCHEMBL28231650 0.97 LMNA (0.44) LMNAMEN1KMT2AMAPTACHE
SCHEMBL20916353 0.97 LMNA (0.44) LMNAMEN1KMT2AMAPTACHE
SCHEMBL28073493 0.93 LMNA (0.41) LMNAMEN1KMT2AMAPTACHE
SCHEMBL27933144 0.93 LMNA (0.41) LMNAMEN1KMT2AMAPTACHE
SCHEMBL27948683 0.93 LMNA (0.41) LMNAMEN1KMT2AMAPTACHE
SCHEMBL28809119 0.91 LMNA (0.40) LMNAMEN1KMT2AMAPTACHE
SCHEMBL27932898 0.91 LMNA (0.40) LMNAMEN1KMT2AMAPTACHE
SCHEMBL27638238 0.91 LMNA (0.40) LMNAMEN1KMT2AMAPTACHE
SCHEMBL27948617 0.91 LMNA (0.40) LMNAMEN1KMT2AMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111587256-B Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2023-05-19 CN claimed
CN-115926076-A Production method and device of polypropylene alloy 北京鑫美格工程设计有限公司 2023-04-07 CN claimed
EP-3583140-B1 SUPPORTED CATALYST SYSTEMS AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-03-08 EP claimed
CN-111587257-B Mixed catalyst system with four metallocenes on a single support 埃克森美孚化学专利公司 2023-02-10 CN claimed
CN-111108130-B Has the advantages ofcontaining-CH2-SiMe3Hybrid catalysts of partially unbridged hafnocenes 埃克森美孚化学专利公司 2022-06-28 CN claimed
CN-110431160-B Supported catalyst system and method of use 埃克森美孚化学专利公司 2021-12-31 CN claimed
CN-108250340-B Metallocene catalyst system and method for catalyzing olefin polymerization by using same 北京引发科技有限公司 2021-03-19 CN claimed
CN-112218900-A Catalyst system comprising two hafnocene catalyst compounds 埃克森美孚化学专利公司 2021-01-12 CN claimed
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN claimed
CN-111587256-A Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2020-08-25 CN claimed
US-6277934-B1 A SYNDIOTACTIC HOMO- OR COPOLYMER FROM A STYRENIC COMPOUND IN THE PRESENCE OF A METALLOCENE OF HIGH, STABLE ACTIVITY COMPRISING A TITANIUM COMPOUND AND AN ORGANIC ALUMINOXY COMPOUND OF SPECIFIC NUCLEAR MAGNETIC RESONANCE SPECTRUM IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-08-21 US claimed
WO-2001019829-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO claimed
WO-2001019828-A2 KINASE INHIBITORS AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO claimed
CN-1260807-A Polymerization method for olefrines BOREALL AS (DK) 2000-07-19 CN claimed
EP-0810231-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2000-01-19 EP claimed
EP-0918757-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1999-06-02 EP claimed
US-5886107-A USING TITANIUM CATALYST, ALKALI METAL HYDRIDE SHELL OIL COMPANY (US) 1999-03-23 US claimed
CN-1196732-A Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors SEARLE & CO (US) 1998-10-21 CN claimed
EP-0810231-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-12-03 EP claimed
WO-1997043268-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1997-11-20 WO claimed