Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.88 |
| ▸ | DRD3 | P35462 | 14/20 | 0.88 |
| ▸ | HTR1A | P08908 | 3/20 | 0.79 |
| ▸ | DRD4 | P21917 | 3/20 | 0.79 |
| ▸ | HTR2A | P28223 | 3/20 | 0.79 |
| ▸ | HTR2C | P28335 | 3/20 | 0.79 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.79 |
| ▸ | HTR7 | P34969 | 2/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.79 |
| ▸ | HRH1 | P35367 | 2/20 | 0.79 |
| ▸ | DRD1 | P21728 | 2/20 | 0.79 |
| ▸ | HTR2B | P41595 | 2/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
| ▸ | DRD5 | P21918 | 1/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.78 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795357 | 0.96 | DRD2 (0.83) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL3410107 | 0.96 | DRD2 (0.83) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL3410104 | 0.96 | DRD2 (0.83) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL22960299 | 0.95 | DRD2 (0.80) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL29353320 | 0.94 | DRD2 (1.00) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL3406923 | 0.94 | DRD2 (1.00) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL3406924 | 0.94 | DRD2 (1.00) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL22302333 | 0.94 | DRD2 (0.78) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL22302320 | 0.94 | DRD2 (0.78) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL30065986 | 0.94 | DRD2 (0.78) | DRD2DRD3HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300883-A1 | SYNTHESIS METHOD FOR CARIPRAZINE | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD (CN) | 2021-09-30 | — | — | US | disclosed |
| EP-3845523-A1 | SYNTHESIS METHOD FOR CARIPRAZINE | Zhejiang Huahai Pharmaceutical Co., Ltd. (CN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020042876-A1 | SYNTHESIS METHOD FOR CARIPRAZINE | 浙江华海药业股份有限公司 | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300883-A1 | SYNTHESIS METHOD FOR CARIPRAZINE | AADAC, HDAC5, PDE12 | DRD2 684/4885DRD3 1145/4885HTR1A 1968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.