SCHEMBL2179588

SCHEMBL2179588

CCCCCC(N)OC(=O)O.[Ni]

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.50
GRIK2 Q13002 2/20 0.50
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
GPR84 Q9NQS5 7/20 0.44
FFAR1 O14842 2/20 0.44
SLC1A3 P43003 1/20 0.43
LAP3 P28838 2/20 0.42
MAPT P10636 1/20 0.42
TP53 P04637 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
OPRM1 P35372 1/20 0.41
FFAR4 Q5NUL3 1/20 0.40
ACE2 Q9BYF1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312180 0.96 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL4630307 0.83 GRIK1 (0.48) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL27922903 0.82 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL27918872 0.82 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL27980592 0.82 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL1401796 0.82 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL5968376 0.82 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL4460936 0.82 GRIK1 (0.47) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL29131411 0.82 GRIK1 (0.50) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL66570 0.80 GRIK1 (0.49) GRIK1GRIK2SLC1A2SLC1A1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194085-A1 METHOD FOR PREPARING AN OLIGOMERIZATION CATALYST COMPRISING A HYDROTHERMAL TREATMENT STEP Evonik Operations GmbH (DE) 2023-06-14 EP disclosed
US-20230173467-A1 Process for producing an oligomerization catalyst having a hydrothermal treatment step EVONIK OPERATIONS GMBH (DE) 2023-06-08 US disclosed
CN-110270337-B Ni-containing catalyst for olefin oligomerization 赢创运营有限公司 2023-05-26 CN disclosed
US-11253844-B2 Oligomerization catalyst and process for the production thereof EVONIK OPERATIONS GMBH (DE) 2022-02-22 US disclosed
US-10882028-B2 Ni-containing catalyst for the oligomerization of olefins EVONIK OPERATIONS GMBH (DE) 2021-01-05 US disclosed
US-10850261-B2 Oligomerization catalyst and process for the production thereof EVONIK OPERATIONS GMBH (DE) 2020-12-01 US disclosed
CN-110270337-A Catalyst containing Ni for olefin oligomerization 赢创德固赛有限公司 2019-09-24 CN disclosed
US-20190283004-A1 OLIGOMERIZATION CATALYST AND PROCESS FOR THE PRODUCTION THEREOF EVONIK DEGUSSA GMBH (DE) 2019-09-19 US disclosed
US-20190283003-A1 OLIGOMERIZATION CATALYST AND PROCESS FOR THE PRODUCTION THEREOF EVONIK DEGUSSA GMBH (DE) 2019-09-19 US disclosed
US-20190283006-A1 NI-CONTAINING CATALYST FOR THE OLIGOMERIZATION OF OLEFINS EVONIK DEGUSSA GMBH (DE) 2019-09-19 US disclosed
US-9387462-B2 Catalyst and method of catalyst manufacture JOHNSON MATTHEY PLC (GB) 2016-07-12 US disclosed
US-20130079568-A1 CATALYST AND METHOD OF CATALYST MANUFACTURE JOHNSON MATTHEY PLC (GB) 2013-03-28 US disclosed
EP-2521617-A2 CATALYST AND METHOD OF CATALYST MANUFACTURE Johnson Matthey PLC (GB) 2012-11-14 EP disclosed
WO-2011080515-A2 CATALYST AND METHOD OF CATALYST MANUFACTURE JOHNSON MATTHEY PLC (GB) 2011-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11253844-B2 Oligomerization catalyst and process for the production thereof C9, C5, C1S GRIK1 3502/4885GRIK2 2758/4885SLC1A2 4730/4885
US-10850261-B2 Oligomerization catalyst and process for the production thereof C9, C5, C1S GRIK1 3502/4885GRIK2 2758/4885SLC1A2 4730/4885
US-20190283003-A1 OLIGOMERIZATION CATALYST AND PROCESS FOR THE PRODUCTION THEREOF C9, C5, C1S GRIK1 3502/4885GRIK2 2758/4885SLC1A2 4730/4885
US-20190283004-A1 OLIGOMERIZATION CATALYST AND PROCESS FOR THE PRODUCTION THEREOF C9, C5, C1S GRIK1 3502/4885GRIK2 2758/4885SLC1A2 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.