Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 6/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715676 | 0.83 | SLCO1B1 (0.79) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL19715511 | 0.83 | SLCO1B1 (0.79) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL19715602 | 0.76 | SLCO1B1 (0.71) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252711 | 0.76 | SLCO1B1 (0.61) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL30625383 | 0.76 | SLCO1B1 (0.61) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22436302 | 0.76 | SLCO1B1 (0.70) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252457 | 0.76 | SLCO1B1 (0.68) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL24044012 | 0.75 | SLCO1B1 (0.64) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252658 | 0.75 | SLCO1B1 (0.64) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252518 | 0.74 | SLCO1B1 (0.53) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666771-B1 | LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3666771-A1 | LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-3472148-B1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2020-03-11 | — | — | EP | disclosed |