Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345151 | 0.83 | CYP19A1 (0.47) | CYP19A1HTTSMN1; SMN2ATMCHRM3 | |
| SCHEMBL21103611 | 0.83 | CYP19A1 (0.44) | CYP19A1HTTSMN1; SMN2ATMCHRM3 | |
| Hydrochloric Acid SCHEMBL185528 | 0.82 | CYP19A1 (0.46) | CYP19A1HTTSMN1; SMN2ATMCHRM3 | |
| SCHEMBL4673661 | 0.82 | CYP19A1 (0.50) | CYP19A1HTTSMN1; SMN2CHRM3NAAA | |
| Hydrochloric Acid SCHEMBL18954396 | 0.82 | CYP19A1 (0.42) | CYP19A1HTTSMN1; SMN2ATMCHRM3 | |
| Hydrochloric Acid SCHEMBL25251995 | 0.81 | MAPT (0.46) | CYP19A1APOBEC3AAPOBEC3GKDM4EHTT | |
| Hydrochloric Acid SCHEMBL18954563 | 0.80 | CYP19A1 (0.49) | CYP19A1HTTSMN1; SMN2CHRM3NAAA | |
| SCHEMBL21305857 | 0.78 | KAT2B (0.36) | CYP19A1SMN1; SMN2ATMCHRM3 | |
| Hydrochloric Acid SCHEMBL29006946 | 0.78 | MAPT (0.35) | CYP19A1APOBEC3AAPOBEC3GKDM4EHTT | |
| SCHEMBL17911018 | 0.78 | F2 (0.33) | F2PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464268-B1 | NOVEL COMPOUNDS | CHIESI FARM SPA (IT) | 2020-03-11 | — | — | EP | disclosed |