Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673661 | 0.98 | CYP19A1 (0.50) | CYP19A1EPHX1NAAACHRM3HTT | |
| Hydrochloric Acid SCHEMBL185528 | 0.98 | CYP19A1 (0.46) | CYP19A1EPHX1NAAACHRM3HTT | |
| Hydrochloric Acid SCHEMBL18954563 | 0.96 | CYP19A1 (0.49) | CYP19A1EPHX1NAAACHRM3HTT | |
| SCHEMBL21103611 | 0.96 | CYP19A1 (0.44) | CYP19A1EPHX1NAAACHRM3HTT | |
| Hydrochloric Acid SCHEMBL18954396 | 0.94 | CYP19A1 (0.42) | CYP19A1EPHX1NAAACHRM3HTT | |
| SCHEMBL16575246 | 0.83 | CYP19A1 (0.45) | CYP19A1EPHX1NAAACHRM3HTT | |
| SCHEMBL21796112 | 0.83 | CYP19A1 (0.35) | CYP19A1NAAACHRM3HTTSMN1; SMN2 | |
| SCHEMBL1682649 | 0.82 | CYP19A1 (0.50) | CYP19A1EPHX1NAAACHRM3HTT | |
| SCHEMBL21305857 | 0.82 | KAT2B (0.36) | CYP19A1CHRM3SMN1; SMN2ATMDPP4 | |
| SCHEMBL24326577 | 0.81 | CYP19A1 (0.35) | CYP19A1CHRM3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112708052-B | Ether viscosity-reducing hydration regulator and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112708056-B | Viscosity-reducing polycarboxylate superplasticizer for concrete member and preparation method thereof | 科之杰新材料集团河南有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112708056-A | Viscosity-reducing polycarboxylate superplasticizer for concrete member and preparation method thereof | 科之杰新材料集团河南有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-112708052-A | Ether viscosity-reducing hydration regulator and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2021-04-27 | — | — | CN | disclosed |
| US-10745428-B2 | Antiviral phosphodiamide prodrugs of tenofovir | IDENIX PHARMACEUTICALS LLC (US) | 2020-08-18 | — | — | US | disclosed |
| US-10736908-B2 | Antiviral aryl-amide phosphodiamide compounds | MERCK SHARP & DOHME CORP. (US) | 2020-08-11 | — | — | US | disclosed |
| US-10449208-B2 | Antiviral prodrugs of tenofovir | MERCK SHARP & DOHME CORP. (US) | 2019-10-22 | — | — | US | disclosed |
| US-20190262365-A1 | ANTIVIRAL ARYL-AMIDE PHOSPHODIAMIDE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-08-29 | — | — | US | disclosed |
| US-20190183912-A1 | ANTIVIRAL PRODRUGS OF TENOFOVIR | MERCK SHARP & DOHME CORP. (US) | 2019-06-20 | — | — | US | disclosed |
| EP-2864318-B1 | 2-AMINOPYRAZINE DERIVATIVES AS CSF-1R KINASE INHIBITORS | MACROPHAGE PHARMA LTD (GB) | 2017-08-09 | — | — | EP | disclosed |
| WO-2010097586-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010043865-A1 | INHIBITORS OF HSP90 | CHROMA THERAPEUTICS LTD (GB) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010043865-A1 | INHIBITORS OF HSP90 | CHROMA THERAPEUTICS LTD (GB) | 2010-04-22 | — | — | WO | disclosed |
| WO-2009141575-A1 | INHIBITORS OF PLK | CHROMA THERAPEUTICS LTD. (GB) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009130475-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AS IKK-BETA SERINE-, THREONINE-PROTEIN KINASE INHIBITORS | CHROMA THERAPEUTICS LTD., (GB) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009106848-A2 | ENZYME AND RECEPTOR MODULATION | CHROMA THERAPEUTICS LTD. (GB) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106844-A1 | INHIBITORS OF P38 MAP KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2009-09-03 | — | — | WO | disclosed |
| EP-1095935-B1 | 6-Hydroxy-5,6-dihydrouracils as herbicides | SUMITOMO CHEMICAL CO (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-6410484-B1 | ACTIVE MATERIAL; CONTROLLING WEEDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1095935-A1 | 6-Hydroxy-5,6-dihydrouracils as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736908-B2 | Antiviral aryl-amide phosphodiamide compounds | PNP, TYMP, DUT | CYP19A1 1127/4885EPHX1 2888/4885NAAA 59/4885 |
| US-20190183912-A1 | ANTIVIRAL PRODRUGS OF TENOFOVIR | PNP, TYMP, HPRT1 | CYP19A1 1189/4885EPHX1 3009/4885NAAA 657/4885 |
| US-10449208-B2 | Antiviral prodrugs of tenofovir | PNP, TYMP, HPRT1 | CYP19A1 1189/4885EPHX1 3009/4885NAAA 657/4885 |
| US-10745428-B2 | Antiviral phosphodiamide prodrugs of tenofovir | PNP, TYMP, PPA1 | CYP19A1 1677/4885EPHX1 2862/4885NAAA 285/4885 |
| US-20190262365-A1 | ANTIVIRAL ARYL-AMIDE PHOSPHODIAMIDE COMPOUNDS | PNP, TYMP, DUT | CYP19A1 1127/4885EPHX1 2888/4885NAAA 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.