Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.31 |
| ▸ | MST1R | Q04912 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | FRK | P42685 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | STK3 | Q13188 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21796216 | 0.93 | RORC (0.31) | RORC | |
| SCHEMBL29774752 | 0.93 | RORC (0.31) | RORC | |
| SCHEMBL21999932 | 0.92 | PIK3CA (0.37) | DDR1AURKB | |
| SCHEMBL21999358 | 0.91 | PIK3CD (0.32) | ACVR1CLK4MST1RCDK8PRKD3 | |
| SCHEMBL21998973 | 0.89 | DDR1 (0.33) | DDR1RORC | |
| SCHEMBL22280577 | 0.86 | RORC (0.35) | DDR1RORCACVR1CLK4MST1R | |
| SCHEMBL18498639 | 0.85 | DDR1 (0.39) | DDR1RORC | |
| SCHEMBL21999354 | 0.85 | PIK3CA (0.34) | AURKB | |
| SCHEMBL20042377 | 0.85 | RORC (0.34) | DDR1RORCACVR1CLK4MST1R | |
| SCHEMBL30051769 | 0.85 | RORC (0.34) | DDR1RORCACVR1CLK4MST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11505553-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2022-11-22 | — | — | US | disclosed |
| US-11089783-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-17 | — | — | US | disclosed |
| EP-3619212-B1 | 2- (HET) ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-20200146293-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-05-14 | — | — | US | disclosed |
| US-20200148686-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-05-14 | — | — | US | disclosed |
| US-20200148686-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-05-14 | — | — | US | disclosed |
| EP-3619212-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | Bayer AG (DE) | 2020-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148686-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | HRH4, AHR, DDT | DDR1 2001/4885RORC 1658/4885ACVR1 525/4885 |
| US-11089783-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | AHR, DDT, CYP8B1 | DDR1 2201/4885RORC 3521/4885ACVR1 668/4885 |
| US-20200146293-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | AHR, DDT, CYP8B1 | DDR1 2201/4885RORC 3521/4885ACVR1 668/4885 |
| US-11505553-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | HRH4, AHR, DDT | DDR1 2001/4885RORC 1658/4885ACVR1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.