SCHEMBL21797135

SCHEMBL21797135

COc1c(Cl)cccc1-c1ccccc1CO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PKM P14618 2/20 0.43
PDCD1 Q15116 2/20 0.42
CD274 Q9NZQ7 2/20 0.42
DPP4 P27487 1/20 0.41
P2RX7 Q99572 3/20 0.40
BAZ2B Q9UIF8 2/20 0.39
BAZ2A Q9UIF9 2/20 0.39
MME P08473 1/20 0.39
CYP2A6 P11509 1/20 0.38
MAPT P10636 2/20 0.37
HTR7 P34969 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9285162 0.85 CSNK2A2 (0.46) KDM4ENPC1RAB9APKMDPP4
SCHEMBL3328387 0.84 KMT2A (0.40) KDM4EPKMMAPTMEN1KMT2A
SCHEMBL21797134 0.83 KDM4E (0.43) KDM4ENPC1RAB9APKMDPP4
SCHEMBL21797050 0.83 KDM4E (0.41) KDM4ENPC1RAB9APKMPDCD1
SCHEMBL10946385 0.78 PDCD1 (0.46) KDM4EPDCD1CD274BAZ2BBAZ2A
SCHEMBL3863811 0.78 DPP4 (0.63) NPC1RAB9APKMPDCD1CD274
SCHEMBL27907980 0.77 CYP2A6 (0.61) KDM4ENPC1RAB9APKMMME
SCHEMBL10436838 0.76 PDCD1 (0.36) KDM4EPDCD1CD274DPP4P2RX7
SCHEMBL19897383 0.75 KDM4E (0.47) KDM4ENPC1RAB9APKMP2RX7
SCHEMBL11122864 0.74 SLC6A2 (0.50) P2RX7MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12171137-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2024-12-17 US disclosed
US-20200083459-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2020-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12171137-B2 Organic electroluminescent materials and devices OXGR1, NR2C2, OCIAD2 KDM4E 2681/4885NPC1 3191/4885RAB9A 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.