SCHEMBL21797134

SCHEMBL21797134

COc1c(Cl)cccc1-c1ccccc1CBr

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PKM P14618 1/20 0.43
DPP4 P27487 1/20 0.41
P2RX7 Q99572 3/20 0.40
HTR7 P34969 1/20 0.37
MAPT P10636 1/20 0.37
CASR P41180 3/20 0.37
MME P08473 1/20 0.36
HTR1A P08908 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CCNT1 O60563 1/20 0.34
CDK9 P50750 1/20 0.34
CYP2A6 P11509 1/20 0.34
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9285162 0.85 CSNK2A2 (0.46) KDM4ENPC1RAB9APKMDPP4
SCHEMBL4904132 0.84 CASR (0.38) KDM4ERAB9AP2RX7MAPTCASR
SCHEMBL30423276 0.84 CASR (0.38) KDM4ERAB9AP2RX7MAPTCASR
SCHEMBL21797135 0.83 KDM4E (0.43) KDM4ENPC1RAB9APKMDPP4
SCHEMBL21797118 0.83 KDM4E (0.41) KDM4ENPC1RAB9APKMP2RX7
SCHEMBL29143297 0.81 HTR2A (0.45) KDM4EP2RX7MEN1KMT2AIDO1
SCHEMBL19897383 0.75 KDM4E (0.47) KDM4ENPC1RAB9APKMP2RX7
SCHEMBL23881811 0.74 TAAR1 (0.36) KDM4EP2RX7MAPTHTR1AADRA1D
SCHEMBL21797044 0.74 DPP4 (0.44) NPC1RAB9APKMDPP4IDO1
SCHEMBL9078093 0.73 ALDH1A1 (0.40) KDM4EMEN1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12171137-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2024-12-17 US disclosed
US-20200083459-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2020-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12171137-B2 Organic electroluminescent materials and devices OXGR1, NR2C2, OCIAD2 KDM4E 2681/4885NPC1 3191/4885RAB9A 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.