Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21797162 | 0.85 | POLB (0.57) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL5069923 | 0.83 | L3MBTL1 (0.59) | SMN1; SMN2NPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL21797171 | 0.82 | POLB (0.62) | NPC1RAB9ACYP1A2CYP2C9KMT2A | |
| SCHEMBL21797194 | 0.81 | POLB (0.65) | NPC1RAB9ACYP1A2CYP2C9KMT2A | |
| SCHEMBL21797192 | 0.80 | POLB (0.63) | NPC1RAB9AKMT2AHTTPOLB | |
| SCHEMBL21797163 | 0.80 | POLB (0.63) | NPC1RAB9AKMT2AHTTPOLB | |
| SCHEMBL10770893 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL3065316 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL3079520 | 0.78 | SMN1; SMN2 (0.83) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5082298 | 0.78 | POLB (0.64) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626773-B1 | RUBBER COMPOSITION FOR TIRE, AND TIRE | BRIDGESTONE CORP (JP) | 2021-12-08 | — | — | EP | disclosed |
| US-20200283613-A1 | RUBBER COMPOSITION FOR TIRES AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-09-10 | — | — | US | disclosed |
| EP-3626773-A1 | RUBBER COMPOSITION FOR TIRE, AND TIRE | Bridgestone Corporation (JP) | 2020-03-25 | — | — | EP | disclosed |
| US-20200079933-A1 | RUBBER COMPOSITION FOR TIRE, AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-03-12 | — | — | US | disclosed |
| CN-110662799-A | Rubber composition for tire and tire | 株式会社普利司通 | 2020-01-07 | — | — | CN | disclosed |