Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 7/20 | 0.56 |
| ▸ | ERBB3 | P21860 | 5/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.44 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176219 | 0.87 | EGFR (0.67) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL12486513 | 0.84 | MEN1 (0.79) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL2177484 | 0.84 | EGFR (0.57) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL3487003 | 0.81 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL3487000 | 0.80 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL30046349 | 0.80 | SCN9A (0.76) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL2174012 | 0.78 | SCN9A (0.61) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL30748838 | 0.78 | MEN1 (0.54) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL12262542 | 0.77 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL12262439 | 0.77 | EGFR (0.67) | MEN1KMT2ANPC1RAB9AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519501-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | Technische Universität Wien (AT) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | disclosed |