Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 6/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 5/20 | 0.48 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.46 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487003 | 0.84 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL30046349 | 0.82 | SCN9A (0.76) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL691344 | 0.82 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL2174012 | 0.81 | SCN9A (0.61) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL2179743 | 0.80 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL691637 | 0.79 | EGFR (0.60) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL691250 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL414719 | 0.79 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL8219021 | 0.78 | NPC1 (0.58) | MEN1KMT2ANPC1RAB9ASCN9A | |
| SCHEMBL2177484 | 0.78 | EGFR (0.57) | MEN1KMT2ANPC1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016296-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016296-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | MEN1 606/4885KMT2A 3318/4885NPC1 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.