Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 18/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178177 | 0.77 | GCK (0.47) | GCK | |
| SCHEMBL2179866 | 0.76 | GSR (0.37) | GSRTXNRD1GCKMEN1KMT2A | |
| SCHEMBL2179056 | 0.74 | GCK (0.47) | GCK | |
| SCHEMBL13477837 | 0.73 | GCK (0.38) | GCK | |
| SCHEMBL2196814 | 0.71 | GCK (0.58) | GCKMEN1KMT2A | |
| SCHEMBL2893943 | 0.71 | GCK (0.40) | GCK | |
| SCHEMBL2197921 | 0.70 | GCK (0.71) | GCK | |
| SCHEMBL2178618 | 0.70 | GCK (0.52) | GCK | |
| SCHEMBL2419513 | 0.70 | GCK (0.39) | GCK | |
| SCHEMBL2195760 | 0.69 | GCK (0.70) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |