Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195760 | 0.87 | GCK (0.70) | GCK | |
| SCHEMBL2197921 | 0.86 | GCK (0.71) | GCK | |
| SCHEMBL2176106 | 0.85 | GCK (0.49) | GCK | |
| SCHEMBL2196267 | 0.85 | GCK (0.70) | GCK | |
| SCHEMBL2179064 | 0.84 | GCK (0.44) | GCKEGLN2EGLN1LNPEP | |
| SCHEMBL2347451 | 0.84 | GCK (0.71) | GCK | |
| SCHEMBL2178177 | 0.81 | GCK (0.47) | GCKLNPEP | |
| SCHEMBL2178444 | 0.81 | GCK (0.50) | GCKLNPEP | |
| SCHEMBL2178622 | 0.78 | NAMPT (0.34) | GCKEGLN2EGLN1LNPEP | |
| SCHEMBL2195664 | 0.78 | GCK (0.47) | GCKLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |