Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | OSBP | P22059 | 1/20 | 0.45 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | RORA | P35398 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388539 | 1.00 | USP2 (0.63) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6388326 | 1.00 | USP2 (0.63) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5344359 | 0.89 | USP2 (0.64) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5339861 | 0.89 | USP2 (0.64) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5341082 | 0.87 | USP2 (0.61) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7797504 | 0.87 | USP2 (0.61) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6279506 | 0.87 | USP2 (0.61) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5345401 | 0.87 | USP2 (0.61) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5340991 | 0.85 | USP2 (0.59) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5339482 | 0.85 | USP2 (0.59) | USP2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3669877-B1 | METHOD FOR PREPARING A STEROL COMPOSITION FROM PUMPKIN SEED OIL | HUNAN ZHONGKEWENTAI BIO TECH CO LTD (CN) | 2024-02-21 | — | — | EP | claimed |
| US-20200085844-A1 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | Hunan Zhongkewentai Bio-tech co.Ltd | 2020-03-19 | — | — | US | claimed |
| EP-3669877-B1 | METHOD FOR PREPARING A STEROL COMPOSITION FROM PUMPKIN SEED OIL | HUNAN ZHONGKEWENTAI BIO TECH CO LTD (CN) | 2024-02-21 | — | — | EP | disclosed |
| US-11065263-B2 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | HUNAN ZHONGKEWENTAI BIO-TECH CO. LTD (CN) | 2021-07-20 | — | — | US | disclosed |
| US-11065263-B2 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | HUNAN ZHONGKEWENTAI BIO-TECH CO. LTD (CN) | 2021-07-20 | — | — | US | disclosed |
| EP-3669877-A1 | STEROL COMPOSITION IN PUMPKIN SEED OIL AND APPLICATION THEREOF, AND DRUG FOR TREATING BENIGN PROSTATIC HYPERPLASIA | Hunan Zhongkewentai Bio-tech Co. Ltd (CN) | 2020-06-24 | — | — | EP | disclosed |
| EP-3669877-A1 | STEROL COMPOSITION IN PUMPKIN SEED OIL AND APPLICATION THEREOF, AND DRUG FOR TREATING BENIGN PROSTATIC HYPERPLASIA | Hunan Zhongkewentai Bio-tech Co. Ltd (CN) | 2020-06-24 | — | — | EP | disclosed |
| US-20200085844-A1 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | Hunan Zhongkewentai Bio-tech co.Ltd | 2020-03-19 | — | — | US | disclosed |
| US-20200085844-A1 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | Hunan Zhongkewentai Bio-tech co.Ltd | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200085844-A1 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | CYP17A1, HSD17B7, BPHL | USP2 2128/4885MEN1 2134/4885KMT2A 4295/4885 |
| US-11065263-B2 | Sterol composition in pumpkin seed oil and application thereof, and drug for treating benign prostatic hyperplasia | CYP17A1, HSD17B7, BPHL | USP2 2128/4885MEN1 2134/4885KMT2A 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.