SCHEMBL21800959

SCHEMBL21800959

COC(N)=S.NC(O)=S.[Zn]

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33
ATR Q13535 1/20 0.33
PTGS2 P35354 1/20 0.33
HPGD P15428 1/20 0.33
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702317 0.96
SCHEMBL9222625 0.96 CA12 (0.39) CA12CA1CA2CA9ALDH1A1
Hydrogen Sulfide SCHEMBL27730689 0.93 CA12 (0.37) CA12CA1CA2CA9ALDH1A1
Ammonia Solution, Strong SCHEMBL8861886 0.93 CA12 (0.37) CA12CA1CA2CA9ALDH1A1
SCHEMBL48320 0.93 CA12 (0.41) CA12CA1CA2CA9ALDH1A1
SCHEMBL27574905 0.93
Benzene SCHEMBL18167281 0.90 ALDH1A1 (0.36) CA12CA1CA2CA9ALDH1A1
Methane SCHEMBL2464824 0.89 CA12 (0.39) CA12CA1CA2CA9ALDH1A1
Methane SCHEMBL4837851 0.89 CA12 (0.39) CA12CA1CA2CA9ALDH1A1
SCHEMBL451827 0.89 CA12 (0.44) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072273-A1 POLYCYCLIC COMPOUND AS CBL-B INHIBITOR 先声再明医药有限公司 2023-05-04 WO disclosed
WO-2020051933-A1 HIGH TEMPERATURE RESISTANT, FLAME-RETARDANT CABLE MATERIAL AND PREPARATION METHOD THEREFOR 淄博齐鼎立专利信息咨询有限公司 2020-03-19 WO disclosed