SCHEMBL21800967

SCHEMBL21800967

c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4ccc(Nc5ccc6[nH]c7ccccc7c6c5)cc4)ccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.44
MMP9 P14780 7/20 0.44
MMP13 P45452 7/20 0.44
MMP8 P22894 5/20 0.44
KDM4E B2RXH2 1/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPK10 P53779 1/20 0.41
MAPK14 Q16539 1/20 0.41
AHR P35869 1/20 0.40
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
KIF11 P52732 2/20 0.39
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28098705 0.93 KDM4E (0.49) MMP2MMP9MMP13MMP8KDM4E
SCHEMBL25117418 0.86 MMP2 (0.52) MMP2MMP9MMP13MMP8KDM4E
SCHEMBL28130739 0.86 AHR (0.53) KDM4EKMT2AAHRESR1ESR2
SCHEMBL15196350 0.86 AHR (0.53) KDM4EKMT2AAHRESR1ESR2
SCHEMBL30602815 0.86 AHR (0.53) KDM4EKMT2AAHRESR1ESR2
SCHEMBL15196325 0.86 AHR (0.53) KDM4EKMT2AAHRESR1ESR2
SCHEMBL15196348 0.86 AHR (0.53) KDM4EKMT2AAHRESR1ESR2
SCHEMBL15196356 0.83 AHR (0.57) KDM4EMTNR1AMTNR1BKMT2AAHR
SCHEMBL30978363 0.81 AHR (0.55) KDM4EKMT2AAHRESR1ESR2
SCHEMBL30978362 0.81 AHR (0.55) KDM4EKMT2AAHRESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020053689-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-03-19 WO disclosed
CN-106206963-A Light-emitting component, light-emitting device, display device, electronic equipment and illuminator 株式会社半导体能源研究所 2016-12-07 CN disclosed