Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.59 |
| ▸ | G6PD | P11413 | 2/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.59 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.44 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.44 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.44 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801953 | 0.86 | NSD2 (0.60) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL21801727 | 0.86 | NSD2 (0.60) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL21801766 | 0.80 | NSD2 (0.59) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL21801709 | 0.79 | NSD2 (0.38) | NSD2G6PDDNMT1S100A4PADI1 | |
| SCHEMBL21801951 | 0.79 | NSD2 (0.38) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL21801711 | 0.79 | NSD2 (0.58) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL21801763 | 0.75 | NSD2 (0.57) | NSD2G6PDDNMT1HKDC1ATG4B | |
| SCHEMBL21801735 | 0.75 | NSD2 (0.53) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL5925143 | 0.75 | NSD2 (1.00) | NSD2G6PDDNMT1S100A4FNTA | |
| SCHEMBL21801780 | 0.74 | NSD2 (0.52) | NSD2G6PDDNMT1S100A4FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | disclosed |