Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.34 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.32 |
| ▸ | MTOR | P42345 | 5/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801746 | 0.88 | NSD2 (0.36) | NSD2G6PDDNMT1 | |
| SCHEMBL21801757 | 0.81 | NSD2 (0.35) | NSD2G6PDDNMT1HKDC1PADI1 | |
| SCHEMBL21801727 | 0.80 | NSD2 (0.60) | NSD2G6PDDNMT1HKDC1PADI1 | |
| SCHEMBL21801773 | 0.79 | PARP10 (0.38) | NSD2G6PDDNMT1 | |
| SCHEMBL21801758 | 0.79 | NSD2 (0.59) | NSD2G6PDDNMT1HKDC1PADI1 | |
| SCHEMBL21801749 | 0.77 | MAPT (0.39) | PLAU | |
| SCHEMBL21801902 | 0.77 | XDH (0.41) | — | |
| SCHEMBL21801715 | 0.74 | PIM2 (0.42) | — | |
| SCHEMBL21801951 | 0.73 | NSD2 (0.38) | NSD2G6PDDNMT1PADI1PADI3 | |
| SCHEMBL21801763 | 0.72 | NSD2 (0.57) | NSD2G6PDDNMT1HKDC1ATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | disclosed |