Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.70 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | SHBG | P04278 | 1/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.63 |
| ▸ | G6PD | P11413 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 1/20 | 0.59 |
| ▸ | GABRD | O14764 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047682 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL15963473 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL3130550 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL3440809 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL2555591 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL13785427 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL11128263 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL20781172 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL20781187 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 | |
| SCHEMBL11250886 | 1.00 | NR1I3 (1.00) | NR1I3CDK5CDK5R1LMNAGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108220387-A | A kind of total bile acid detection kit | 潍坊市康华生物技术有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-1322130-A | Inhibition of type 3 alpha-hydroxysteroid dehydrogenase | ENDORECH INC (CA) | 2001-11-14 | — | — | CN | claimed |
| EP-3180424-B1 | 3ALPHA-HYDROXYSTERIOD DEHYDROGENASE MUTANTS AND METHOD FOR PRODUCING URSODEOXYCHOLIC ACID | PHARMAZELL GMBH (DE) | 2020-03-18 | — | — | EP | disclosed |
| CN-109082419-A | A kind of 3alpha-Hydroxysteroid dehydrogenase mutant, coding nucleotide sequence and kit | 深圳上泰生物工程有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-105936897-A | Novel 7beta-hydroxysteroid dehydrogenases and their use | 细胞制药有限公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-104388440-A | DNA sequence for expressing 3 alpha-hydroxysteroid dehydrogenase in Pseudomonas aeruginosa | UNIV SICHUAN | 2015-03-04 | — | — | CN | disclosed |
| CN-101698834-B | 3 alpha-hydroxysteroid dehydrogenase and nucleotide sequence, recombinant vector, recombinant host cell and kit thereof | BEIJING LEADMAN BIOCHEMISTRY CO LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-101698834-A | 3 alpha-hydroxysteroid dehydrogenase, nucleotide sequence thereof, recombinant vector thereof, recombinant host cells thereof and kit | BEIJING LEADMAN BIOCHEMISTRY C | 2010-04-28 | — | — | CN | disclosed |
| CN-1429104-A | Inhibitors of 17 beta-hydroxysteroid dehydrogenase type 5 and 3 and methods of use thereof | ENDORECH INC (CA) | 2003-07-09 | — | — | CN | disclosed |
| CN-1322130-A | Inhibition of type 3 alpha-hydroxysteroid dehydrogenase | ENDORECH INC (CA) | 2001-11-14 | — | — | CN | disclosed |