Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21805185 | 0.89 | DGKA (0.46) | DGKAP2RY10GPR34PLA2G2AENPP2 | |
| SCHEMBL17533548 | 0.81 | DGKA (0.34) | DGKAP2RY10GPR34ENPP2LPAR1 | |
| SCHEMBL18429952 | 0.81 | DGKA (0.65) | DGKAP2RY10GPR34PLA2G2ADNM1 | |
| SCHEMBL27894869 | 0.78 | DGKA (0.61) | DGKAPLA2G2ADNM1 | |
| SCHEMBL27872169 | 0.78 | DGKA (0.65) | DGKAPLA2G2ADNM1 | |
| SCHEMBL8815475 | 0.78 | DGKA (0.65) | DGKAPLA2G2ADNM1 | |
| Cetyl Palmitate SCHEMBL8815494 | 0.78 | DGKA (0.65) | DGKAPLA2G2ADNM1 | |
| SCHEMBL187111 | 0.78 | DGKA (0.59) | DGKAP2RY10PLA2G2ADNM1 | |
| SCHEMBL27872160 | 0.78 | DGKA (0.65) | DGKAPLA2G2ADNM1 | |
| SCHEMBL9637091 | 0.78 | DGKA (0.65) | DGKAPLA2G2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853213-A1 | SHIELDING AGENTS AND THEIR USE | Endocyte, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061293-A1 | SHIELDING AGENTS AND THEIR USE | ENDOCYTE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |