Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | AKT1 | P31749 | 10/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22534527 | 0.86 | NAAA (0.37) | NAAAAKT1 | |
| SCHEMBL30468892 | 0.80 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL11359306 | 0.74 | CYP1A2 (0.34) | AKT1 | |
| SCHEMBL9299912 | 0.74 | AKT1 (0.34) | AKT1EPHX1 | |
| SCHEMBL5645678 | 0.73 | NAAA (0.39) | NAAAAKT1 | |
| SCHEMBL5646098 | 0.73 | NAAA (0.39) | NAAAAKT1 | |
| SCHEMBL5650450 | 0.73 | NAAA (0.39) | NAAAAKT1 | |
| SCHEMBL5644160 | 0.73 | NAAA (0.39) | NAAAAKT1 | |
| SCHEMBL5645017 | 0.73 | NAAA (0.39) | NAAAAKT1 | |
| SCHEMBL5646432 | 0.73 | NAAA (0.39) | NAAAAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596053-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ORGANOVO INC (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-3852736-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | Metacrine, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061118-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061117-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061116-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |