Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272285 | 0.90 | LMNA (0.51) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL1896532 | 0.88 | LMNA (0.49) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL31070840 | 0.88 | LMNA (0.49) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL27989845 | 0.87 | PDE3A (0.47) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL28878518 | 0.87 | PDE3A (0.47) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL7775032 | 0.87 | LMNA (0.48) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL6385398 | 0.86 | LMNA (0.47) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| Phosphoric Acid SCHEMBL16655013 | 0.86 | LMNA (0.47) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| Phosphoric Acid SCHEMBL21645281 | 0.86 | LMNA (0.47) | LMNAPDE3AMTORPDE4DSLC29A1 | |
| SCHEMBL15239320 | 0.86 | LMNA (0.47) | LMNAPDE3AMTORPDE4DSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079501-A1 | PRODRUG BASED ON CYTARABINE STRUCTURE AS WELL AS SYNTHESIZING METHOD AND APPLICATION THEREOF | 济南圣鲁金药物技术开发有限公司 (CN) | 2011-07-07 | — | — | WO | disclosed |
| CN-102115485-A | Prodrug based on cytosine arabinoside structure, and synthesis method and application thereof | SANLUGEN PHARMATECH | 2011-07-06 | — | — | CN | disclosed |
| CN-101525361-B | Prodrug based on gemcitabine structure as well as synthesizing method and application thereof | JINAN SHENGLUJIN PHARMACEUTICAL TECHNOLOGY DEV CO LTD | 2010-11-17 | — | — | CN | disclosed |
| CN-101525361-A | Prodrug based on gemcitabine structure as well as synthesizing method and application thereof | SANLUGEN PHARMATECH DEV CO LTD | 2009-09-09 | — | — | CN | disclosed |