Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL21806751

N.OC(=S)c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPT P10636 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
HSP90AA1 P07900 1/20 0.46
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
TSHR P16473 2/20 0.45
DAO P14920 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
EPHX1 P07099 1/20 0.41
POLB P06746 2/20 0.41
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
F12 P00748 1/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL15282156 0.97 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL37018 0.97
Thiobenzoic Acid SCHEMBL160729 0.97 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL28199536 0.97 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL11305253 0.93 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL2165933 0.93 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL284149 0.93 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL20741485 0.93 MAPT (0.48) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL584244 0.93 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
Thiobenzoic Acid SCHEMBL11330586 0.93 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805384-A Method for preparing D-biotin intermediate 帝斯曼知识产权资产管理有限公司 2022-07-29 CN claimed
US-12312343-B2 Rotomeric isomers of 4-alkyl-5-heteroaryl-3H-1,2-dithiole-3-thiones ST IP HOLDING AG (CH) 2025-05-27 US disclosed
EP-3853223-B1 ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2- DITHIOLE-3-THIONES ST IP HOLDING AG (CH) 2025-01-01 EP disclosed
US-20230255961-A1 Rotomeric Isomers of 4-Alkyl-5-Heteroaryl-3H-1,2-Dithiole-3-Thiones ZPNE GROUP GMBH (CH) 2023-08-17 US disclosed
CN-112121819-B Preparation method of cadmium sulfide self-doped titanium dioxide composite catalyst 中国石油化工股份有限公司 2023-08-04 CN disclosed
CN-114805384-A Method for preparing D-biotin intermediate 帝斯曼知识产权资产管理有限公司 2022-07-29 CN disclosed
CN-114072091-A Wound closure system including an incise drape filled with a releasable antimicrobial agent for reducing surgical site infection 爱惜康股份有限公司 2022-02-18 CN disclosed
CN-113694068-A Rotamers of 4-alkyl-5-heteroaryl-3H-1, 2-dithiole-3-thiones ST知识产权控股公司 2021-11-26 CN disclosed
WO-2021186244-A1 ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2-DITHIOLE-3-THIONES ST IP HOLDING AG (CH) 2021-09-23 WO disclosed
EP-3853223-A1 ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2- DITHIOLE-3-THIONES ST IP Holding AG (CH) 2021-07-28 EP disclosed
CN-113166127-A Rotamers of 4-alkyl-5-heteroaryl-3H-1, 2-dithiole-3-thiones ST知识产权控股公司 2021-07-23 CN disclosed
US-20210206751-A1 Rotomeric Isomers of 4-alkyl-5-Heteroaryl-3H-1,2-Dithiole-3-Thiones SUPPORTIVE THERAPEUTICS AG (CH) 2021-07-08 US disclosed
CN-112121819-A Preparation method of cadmium sulfide self-doped titanium dioxide composite catalyst 中国石油化工股份有限公司 2020-12-25 CN disclosed
WO-2020058767-A1 ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2- DITHIOLE-3-THIONES ST IP HOLDING AG (CH) 2020-03-26 WO disclosed