Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12520164 | 0.87 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14960095 | 0.83 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14065065 | 0.83 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL5083672 | 0.81 | MAPT (0.83) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11698958 | 0.81 | POLB (0.59) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL257300 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6824108 | 0.80 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8129829 | 0.80 | HSP90AA1 (0.53) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL28513748 | 0.79 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14951043 | 0.79 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358222-A1 | MOLECULARLY IMPRINTED SMART POLYMERS (MISPs) | Salio Nanotechnologies Ltd. (IL) | 2011-08-24 | — | — | EP | disclosed |
| US-20110166297-A1 | MOLECULARLY IMPRINTED SMART POLYMERS (MISPs) | Sailo Nanotechnologies Ltd. (IL) | 2011-07-07 | — | — | US | disclosed |
| WO-2010029541-A1 | MOLECULARLY IMPRINTED SMART POLYMERS (MISPs) | SALIO NANOTECHNOLOGIES LTD. (IL) | 2010-03-18 | — | — | WO | disclosed |
| US-6136968-A | PHOTOCHROMIC, TRANSPARENT | TRANSITIONS OPTICAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| EP-0915886-A1 | NOVEL HOMOAZAADAMANTANE SPIROOXAZINES AND USE THEREOF IN OPHTHALMIC OPTICS | Transitions Optical, Inc. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004563-A1 | NOVEL HOMOAZAADAMANTANE SPIROOXAZINES AND USE THEREOF IN OPHTHALMIC OPTICS | TRANSITIONS OPTICAL INC. (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166297-A1 | MOLECULARLY IMPRINTED SMART POLYMERS (MISPs) | MSI2, SLIRP, BRAP | MEN1 470/4885KMT2A 1647/4885MAPT 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.