Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960095 | 0.92 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14951043 | 0.87 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5351787 | 0.86 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5351789 | 0.86 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14960078 | 0.82 | ALDH1A1 (0.57) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13863125 | 0.82 | NQO2 (0.73) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL2180737 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL20886079 | 0.81 | NQO2 (0.60) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL21784228 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL12520164 | 0.80 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611869-B1 | DYE-ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2012028245-A1 | DYE-ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |