Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135812 | 0.97 | — | — | |
| Bromide SCHEMBL789378 | 0.84 | DNM1 (0.31) | — | |
| Bromide SCHEMBL29265109 | 0.82 | CYP2D6 (0.30) | — | |
| Bromide SCHEMBL22398204 | 0.82 | CYP2D6 (0.30) | — | |
| SCHEMBL1726666 | 0.81 | ODC1 (0.31) | — | |
| Bromide SCHEMBL28376789 | 0.80 | DNM1 (0.39) | — | |
| SCHEMBL11046183 | 0.80 | — | — | |
| SCHEMBL326026 | 0.79 | CYP2D6 (0.32) | — | |
| Water SCHEMBL1725502 | 0.79 | ODC1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL18420902 | 0.79 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321222-B1 | A NOVEL MOLECULAR SIEVE COMPOSITION EMM-12 AND A PROCESS OF USING THE SAME | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-01-02 | — | — | EP | disclosed |
| US-8704025-B2 | Molecular sieve composition EMM-12, a method of making and a process of using the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-20110166401-A1 | Novel Molecular Sieve Composition EMM-12, A Method of Making and a Process of Using the Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-07-07 | — | — | US | disclosed |