Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636624 | 0.92 | ABCB11 (0.39) | SLCO1B1ABCB11PIK3CDPIK3R1PIK3CA | |
| SCHEMBL28466104 | 0.84 | SLCO1B1 (0.49) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22576697 | 0.84 | SLCO1B1 (0.49) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL21807793 | 0.83 | SLCO1B1 (0.48) | SLCO1B1ABCB11PIK3CDABCC3ABCC4 | |
| SCHEMBL19715709 | 0.83 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL23116983 | 0.81 | SLCO1B1 (0.39) | SLCO1B1ABCB11PIK3CDABCC3ABCC4 | |
| SCHEMBL22576667 | 0.81 | SLCO1B1 (0.39) | SLCO1B1ABCB11PIK3CDABCC3ABCC4 | |
| SCHEMBL22463665 | 0.81 | SLCO1B1 (0.39) | SLCO1B1ABCB11PIK3CDABCC3ABCC4 | |
| SCHEMBL22576669 | 0.81 | SLCO1B1 (0.39) | SLCO1B1ABCB11PIK3CDABCC3ABCC4 | |
| SCHEMBL22463667 | 0.81 | SLCO1B1 (0.52) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3852746-A1 | CYCLOPENTYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020060915-A1 | CYCLOPENTYL ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-26 | — | — | WO | disclosed |