Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21807976 | 0.74 | NPC1 (0.33) | RAB9ANPC1ATM | |
| SCHEMBL21807974 | 0.73 | KDM5C (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL21808031 | 0.73 | HDAC8 (0.34) | L3MBTL1 | |
| SCHEMBL12022152 | 0.68 | CYP19A1 (0.62) | RAB9AMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL21808097 | 0.68 | SPHK2 (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL21807936 | 0.68 | ACACB (0.39) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL21524622 | 0.67 | — | — | |
| Bromide SCHEMBL1883296 | 0.67 | CYP19A1 (0.60) | RAB9AMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL19723347 | 0.66 | ALOX5 (0.60) | LMNARAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17697510 | 0.66 | CYP19A1 (0.58) | RAB9AMEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020060963-A1 | 1, 3, 4-OXADIAZOLE DERIVATIVES AND USES THEREOF | ALXERION BIOTECH CORP. (US) | 2020-03-26 | — | — | WO | disclosed |