Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34473910 | 0.84 | KMT2A (0.37) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL21886657 | 0.81 | ALOX15 (0.37) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL426418 | 0.79 | CNR2 (0.37) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL24906856 | 0.78 | KMT2A (0.40) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL18497293 | 0.77 | KMT2A (0.39) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL23326750 | 0.77 | KMT2A (0.42) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL980372 | 0.77 | ADORA1 (0.39) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL1909089 | 0.77 | CNR2 (0.37) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR | |
| SCHEMBL17628821 | 0.76 | GAA (0.42) | KMT2AL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL2958409 | 0.75 | USP2 (0.36) | KMT2AL3MBTL1ALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853220-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | Suzhou Zanrong Pharma Limited (CN) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020057511-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | SUZHOU ZANRONG PHARMA LIMITED (CN) | 2020-03-26 | — | — | WO | disclosed |