Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131116 | 0.85 | MAPT (0.67) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL195190 | 0.85 | MAPT (0.67) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL11141346 | 0.84 | KIF11 (0.57) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL9935634 | 0.82 | KIF11 (0.55) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30357992 | 0.82 | MAPT (0.55) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL14689281 | 0.82 | MAPT (0.55) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8935716 | 0.81 | MAPT (0.54) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL11577428 | 0.81 | KIF11 (0.53) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL1735965 | 0.81 | KIF11 (0.53) | KIF11MAPTMAPK1NPSR1ALDH1A1 | |
| SCHEMBL9935631 | 0.81 | KIF11 (0.53) | KIF11MAPTMAPK1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220120753-A1 | METHOD FOR DETERMINING PROGNOSIS OF CANCER | THE UNIVERSITY OF TOKYO (JP) | 2022-04-21 | — | — | US | disclosed |
| WO-2020059850-A1 | METHOD FOR DETERMINING PROGNOSIS OF CANCER | 国立大学法人東京大学 | 2020-03-26 | — | — | WO | disclosed |
| CN-102816107-B | Carbazole derivative and preparation method and use thereof | UNIV SOUTHEAST | 2015-06-03 | — | — | CN | disclosed |
| CN-102816107-A | Carbazole derivative and preparation method and use thereof | UNIV SOUTHEAST | 2012-12-12 | — | — | CN | disclosed |