Arginine

Arginine

SCHEMBL21808680

N=C(N)NCCCC(N)C(=O)[O-].[K+]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACES1PR1S1PR4S1PR5

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.39
▸ OTC P00480 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ DDAH1 O94760 1/20 0.36
▸ NPY4R P50391 7/20 0.36
▸ NPY1R P25929 5/20 0.36
▸ NPY2R P49146 4/20 0.36
▸ NPY5R Q15761 4/20 0.36
▸ GNAI3 P08754 1/20 0.34
▸ GNAO1 P09471 1/20 0.34
▸ GNAI1 P63096 1/20 0.34
▸ NOS1 P29475 3/20 0.33
▸ NOS3 P29474 2/20 0.33
▸ NOS2 P35228 2/20 0.33
▸ RRM1 P23921 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL2589529 1.00 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL4273378 0.98 DPP7 (0.40) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL7713117 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL15111154 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL5653610 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL6711066 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL16194704 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL3749742 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL7154973 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL1766115 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024019201-A1 FREEZE-DRIED FEMININE CLEANSER COMPRISING NATURAL EXTRACT AS ACTIVE INGREDIENT (주)레이디하우스 2024-01-25 — — WO disclosed
WO-2023234698-A1 SKIN IMPROVEMENT COMPOSITION CONTAINING MUGWORT-DERIVED EXOSOME AS ACTIVE INGREDIENT (주)웰에이징엑소바이오 2023-12-07 — — WO disclosed
WO-2020060072-A1 COSMETIC COMPOSITION COMPRISING THYME EXTRACT AND DENDROPANAX MORBIFERUS EXTRACT 농업회사법인(주)제주우다 2020-03-26 — — WO disclosed
Send feedback