Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 7/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL4273378 | 0.98 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL7713117 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL309164 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL15111154 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL3749742 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL16194704 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL1766115 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL7154973 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL21808680 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL5149122 | 0.96 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4336593-B1 | POSITIVE ELECTRODE ACTIVE MATERIAL, PREPARATION METHOD THEREFOR AND A POSITIVE ELECTRODE PLATE COMPRISING SAME | CONTEMPORARY AMPEREX TECHNOLOGY HONG KONG LTD (HK) | 2026-04-15 | — | — | EP | claimed |
| EP-4120394-B1 | LITHIUM MANGANESE OXIDE POSITIVE ELECTRODE ACTIVE MATERIAL, POSITIVE ELECTRODE PLATE CONTAINING SAME, SECONDARY BATTERY AND BATTERY MODULE | CONTEMPORARY AMPEREX TECHNOLOGY CO LTD (CN) | 2023-09-20 | — | — | EP | claimed |
| CN-115282925-B | Three-dimensional graphene/clay composite aerogel for water treatment | 山东第一医科大学(山东省医学科学院) | 2023-08-22 | — | — | CN | claimed |
| US-20040161449-A1 | Formulation and method for reduction of stress in meat-producing animals | SMOTHERS DON L (US) | 2004-08-19 | — | — | US | claimed |
| WO-2003013495-A1 | FORMULATION AND METHOD FOR REDUCTION OF STRESS IN MEAT-PRODUCING ANIMALS | SMOTHERS DON L (US) | 2003-02-20 | — | — | WO | claimed |
| CN-118703010-A | Physical and chemical synergistic crosslinked high-strength hydrogel and preparation method and application thereof | 西南民族大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-118265520-A | Shear thinning composition for ablation | 波士顿科学国际有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-115282925-B | Three-dimensional graphene/clay composite aerogel for water treatment | 山东第一医科大学(山东省医学科学院) | 2023-08-22 | — | — | CN | disclosed |
| CN-115212227-B | Application of lithioalga soil as effective component in preparing nerve injury repair product | 浙江大学 | 2023-08-18 | — | — | CN | disclosed |
| WO-2023151775-A1 | A PROCESS FOR REVERSIBLE HYDROGEN STORAGE VIA AMINO ACID FORMATE ION PAIRS BY HYDROGENATION OF CARBON DIOXIDE | APEX ENERGY TETEROW GMBH (DE) | 2023-08-17 | — | — | WO | disclosed |
| CN-115990287-A | Nano composite hydrogel, ammonia-sugar-loaded nano lithium alginate soil-wheat protein composite hydrogel, and preparation methods and application thereof | 中国人民解放军海军军医大学第一附属医院 | 2023-04-21 | — | — | CN | disclosed |
| CN-113087003-B | Carbon dioxide absorption and utilization method and application thereof | 国家能源投资集团有限责任公司 | 2022-12-09 | — | — | CN | disclosed |
| US-9957230-B2 | Synergistic compositions | CADILA HEALTHCARE LIMITED (IN) | 2018-05-01 | — | — | US | disclosed |
| US-20170320823-A1 | SYNERGISTIC COMPOSITIONS | ZYDUS LIFESCIENCES LIMITED (IN) | 2017-11-09 | — | — | US | disclosed |
| US-9656954-B2 | Synergistic compositions | CADILA HEALTHCARE LIMITED (IN) | 2017-05-23 | — | — | US | disclosed |
| EP-3120845-A1 | SYNERGISTIC COMPOSITIONS | Cadila Healthcare Limited (IN) | 2017-01-25 | — | — | EP | disclosed |
| EP-3016650-A1 | SYNERGISTIC COMPOSITIONS | Cadila Healthcare Limited (IN) | 2016-05-11 | — | — | EP | disclosed |
| US-20160068484-A1 | SYNERGISTIC COMPOSITIONS | CADILA HEALTHCARE LIMITED (IN) | 2016-03-10 | — | — | US | disclosed |
| WO-2015001573-A9 | SYNERGISTIC COMPOSITIONS | CADILA HEALTHCARE LIMITED (IN) | 2016-02-25 | — | — | WO | disclosed |
| WO-2015001573-A1 | SYNERGISTIC COMPOSITIONS | CADILA HEALTHCARE LIMITED (IN) | 2015-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320823-A1 | SYNERGISTIC COMPOSITIONS | DPP4, PPARD, DPP7 | DPP7 3/4885OTC 3882/4885ALOX15 1574/4885 |
| US-20160068484-A1 | SYNERGISTIC COMPOSITIONS | DPP4, DPP7, PPARD | DPP7 2/4885OTC 3154/4885ALOX15 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.