⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129980 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL6130000 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL990356 | 0.73 | — | — | |
| SCHEMBL5181293 | 0.73 | — | — | |
| SCHEMBL8688833 | 0.73 | — | — | |
| SCHEMBL8691719 | 0.73 | — | — | |
| SCHEMBL8759001 | 0.72 | — | — | |
| SCHEMBL25385810 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL12018888 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8691278 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156621-A1 | ABSORBENT SOLUTION CONTAINING A DEGRADATION SULPHUR-CONTAINING INHIBITOR HAVING A CARBOXYL GROUP AND METHOD FOR LIMITING THE DEGRADATION OF AN ABSORBENT SOLUTION | IFP (FR) | 2009-12-30 | — | — | WO | claimed |
| CN-118206533-A | N-pyridazine pyrazole amide compounds | 湖南化工研究院有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3533436-B1 | COMPOSITIONS COMPRISING MENTHOL, ISOBORNYL BUTYRATE AND APRITONE | PROCTER & GAMBLE (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-1020444-A1 | 6-PHENOXYPICOLINIC ACID, ALKYLIDENEHYDRAZIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-4918231-A | REACTING A SILYLATED CYANOHYDRIN WITH GRIGNARD REAGENT; TREATING WITH REDUCING AGENT; HYDROLYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0170517-B1 | PROCESS FOR THE PRODUCTION OF 1,2-AMINO ALCOHOLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0170517-A2 | Process for the production of 1,2-amino alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4155933-A | Process for halogenation of aldehydes and production of oximes therefrom | ALLIED CHEMICAL CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4101583-A | Alpha-methylthio-alpha-(2-aminophenyl) acetaldehyde diloweralkyl acetals | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4096187-A | Process for halogenation of aldehydes and production of oximes therefrom | ALLIED CHEMICAL CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |
| US-4080341-A | Carbazolenine and indole compounds | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4067875-A | Certain N-phenyl or N-pyridyl aza sulfonium salts | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3992392-A | Synthesis of indoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-11-16 | — | — | US | disclosed |