Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6927040 | 0.82 | TDP1 (0.36) | TDP1LAP3TSHRSLC1A3SLC1A2 | |
| SCHEMBL11762860 | 0.81 | TDP1 (0.60) | TDP1LAP3LMNAALOX15BLM | |
| Ethyl Chloride SCHEMBL15846117 | 0.78 | — | — | |
| Propane SCHEMBL22974974 | 0.77 | — | — | |
| Propane SCHEMBL28309137 | 0.77 | TDP1 (0.80) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL861814 | 0.77 | — | — | |
| SCHEMBL5941026 | 0.77 | TDP1 (0.48) | TDP1 | |
| Ethylamine SCHEMBL6856120 | 0.75 | — | — | |
| Alcohol SCHEMBL821322 | 0.75 | — | — | |
| Butane SCHEMBL644175 | 0.75 | TDP1 (0.75) | TDP1LMNAALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233715-A1 | SMALL HIGHLY UNIFORM NANOMEDICINE COMPOSITIONS FOR THERAPEUTIC, IMAGING AND THERANOSTIC APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-07-27 | — | — | US | disclosed |
| EP-3849404-A1 | SMALL HIGHLY UNIFORM NANOMEDICINE COMPOSITIONS FOR THERAPEUTIC, IMAGING AND THERANOSTIC APPLICATIONS | The Regents Of The University Of Michigan (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20200101176-A1 | Small Highly Uniform Nanomedicine Compositions for Therapeutic, Imaging and Theranostic Applications | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-04-02 | — | — | US | disclosed |
| WO-2020056333-A1 | SMALL HIGHLY UNIFORM NANOMEDICINE COMPOSITIONS FOR THERAPEUTIC, IMAGING AND THERANOSTIC APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-03-19 | — | — | WO | disclosed |