Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811079 | 0.82 | TDP1 (0.55) | TDP1LAP3SLC1A3SLC1A2SLC1A1 | |
| Methacrylic Acid SCHEMBL28569841 | 0.81 | TDP1 (0.39) | TDP1GRIK1GRIK2GRM1GRM2 | |
| Methacrylic Acid SCHEMBL27777455 | 0.81 | TDP1 (0.39) | TDP1GRIK1GRIK2GRM1GRM2 | |
| Methacrylic Acid SCHEMBL28909098 | 0.80 | SLC7A5 (0.43) | TDP1GRIK1GRIK2GRM1GRM2 | |
| Methacrylic Acid SCHEMBL15102966 | 0.80 | TDP1 (0.43) | TDP1GRIK1GRIK2GRM1GRM2 | |
| Methacrylic Acid SCHEMBL28979894 | 0.79 | TDP1 (0.38) | TDP1GRIK1GRIK2GRM1GRM2 | |
| Methacrylic Acid SCHEMBL28165818 | 0.77 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2SLC1A3 | |
| Methacrylic Acid SCHEMBL9788914 | 0.77 | TDP1 (0.42) | TDP1SLC7A5TGFBR1TSHRTET2 | |
| Methacrylic Acid SCHEMBL5158803 | 0.77 | — | — | |
| Methacrylic Acid SCHEMBL203065 | 0.76 | TGFBR1 (0.31) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852140-B1 | METHODS FOR MAKING HARDLY SOLUBLE MEDICINE AMORPHOUS | NISSAN CHEMICAL IND LTD (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-1356807-A2 | Method for converting sparingly water-soluble medical substance to amorphous state | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6462093-B1 | Method for converting sparingly water-soluble medical substance to amorphous state | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0852140-A1 | METHODS FOR MAKING HARDLY SOLUBLE MEDICINE AMORPHOUS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-07-08 | — | — | EP | disclosed |