Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | WNT1 | P04628 | 3/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21812572 | 0.94 | EGFR (0.35) | EGFRDYRK1AGSK3BWNT1AXL | |
| SCHEMBL21812564 | 0.91 | TNKS (0.35) | EGFRDYRK1AGSK3BWNT1KDR | |
| SCHEMBL21812994 | 0.90 | KDR (0.46) | EGFRKDR | |
| SCHEMBL21812593 | 0.87 | NAMPT (0.36) | DYRK1AGSK3BWNT1 | |
| SCHEMBL21813041 | 0.83 | PAICS (0.40) | — | |
| SCHEMBL21834612 | 0.82 | SMN1; SMN2 (0.45) | EGFRDYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL21812598 | 0.82 | ACACB (0.39) | — | |
| SCHEMBL21812764 | 0.81 | NPC1 (0.45) | DYRK1AGSK3B | |
| SCHEMBL21812686 | 0.81 | MAPK1 (0.43) | — | |
| SCHEMBL21813017 | 0.80 | CHEK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | claimed |
| EP-3628672-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | claimed |
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| EP-3628672-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | disclosed |