Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834708 | 0.94 | RAB9A (0.44) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834566 | 0.87 | RAB9A (0.47) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21812757 | 0.82 | EGFR (0.39) | EGFRKDRDYRK1AGSK3BWNT1 | |
| SCHEMBL21834671 | 0.80 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834645 | 0.80 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834561 | 0.79 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834551 | 0.79 | GRM1 (0.57) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834573 | 0.78 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834637 | 0.78 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 | |
| SCHEMBL21834679 | 0.76 | RAB9A (0.43) | SMN1; SMN2NPC1RAB9ALMNAUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | claimed |
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |