Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 6/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052888 | 0.85 | HDAC3 (0.45) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL8041524 | 0.82 | HDAC3 (0.47) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL18136859 | 0.82 | HDAC3 (0.47) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL8053542 | 0.81 | HDAC3 (0.46) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL17136360 | 0.81 | HDAC3 (0.48) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL17371391 | 0.81 | SIRT1 (0.46) | HDAC3HDAC1CA1CA2PTPRB | |
| SCHEMBL18605667 | 0.80 | HDAC3 (0.45) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL28684742 | 0.79 | HDAC3 (0.45) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL16020352 | 0.77 | HDAC3 (0.48) | HDAC3HDAC1HDAC6CA12CA1 | |
| SCHEMBL215719 | 0.77 | HDAC3 (0.51) | HDAC3HDAC1HDAC6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| EP-3628672-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | disclosed |