Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814475 | 0.82 | TDP1 (0.52) | KAT2BTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL21814501 | 0.82 | TDP1 (0.46) | KAT2BTDP1APPMAPK1L3MBTL1 | |
| SCHEMBL21886954 | 0.81 | KAT2B (0.50) | KAT2B | |
| SCHEMBL21814458 | 0.80 | KAT2B (0.50) | KAT2BTDP1APPMAPK1L3MBTL1 | |
| SCHEMBL21886953 | 0.80 | TDP1 (0.44) | KAT2BTDP1APPMAPK1L3MBTL1 | |
| SCHEMBL28450115 | 0.76 | TDP1 (0.64) | TDP1APPMAPK1L3MBTL1MEN1 | |
| SCHEMBL304176 | 0.75 | TDP1 (0.78) | TDP1APPMAPK1L3MBTL1CASP1 | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.74 | TDP1 (0.75) | TDP1APPMAPK1L3MBTL1CASP1 | |
| SCHEMBL28207503 | 0.74 | TDP1 (0.75) | TDP1APPMAPK1L3MBTL1CASP1 | |
| Bicarbonate SCHEMBL7699565 | 0.74 | TDP1 (0.75) | TDP1APPMAPK1L3MBTL1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240350657-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2024-10-24 | — | — | US | disclosed |
| EP-3856258-B1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PF MEDICAMENT (FR) | 2024-07-31 | — | — | EP | disclosed |
| US-12011485-B2 | Sulfomaleimide-based linkers and corresponding conjugates | PIERRE FABRE MEDICAMENT (FR) | 2024-06-18 | — | — | US | disclosed |
| US-20220023438-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2022-01-27 | — | — | US | disclosed |
| US-20220023438-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2022-01-27 | — | — | US | disclosed |
| EP-3856258-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220023438-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | CSGALNACT1, CD44, IGLV6-57 | KAT2B 1943/4885TDP1 4308/4885APP 4712/4885 |
| US-12011485-B2 | Sulfomaleimide-based linkers and corresponding conjugates | CSGALNACT1, CD44, IGLV6-57 | KAT2B 1943/4885TDP1 4308/4885APP 4712/4885 |
| US-20240350657-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | STS, SULT1E1, CD44 | KAT2B 2119/4885TDP1 4212/4885APP 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.