Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814501 | 0.89 | TDP1 (0.46) | TDP1KAT2BMAPTMAPK1L3MBTL1 | |
| SCHEMBL21814457 | 0.80 | KAT2B (0.48) | TDP1KAT2BMAPTMAPK1L3MBTL1 | |
| SCHEMBL21814458 | 0.76 | KAT2B (0.50) | TDP1KAT2BMAPTLMNAMAPK1 | |
| SCHEMBL305162 | 0.74 | MAPT (0.68) | TDP1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL26023562 | 0.74 | MAPT (0.68) | TDP1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28450115 | 0.74 | TDP1 (0.64) | TDP1MAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL304176 | 0.74 | TDP1 (0.78) | TDP1MAPTLMNAMAPK1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.72 | TDP1 (0.75) | TDP1MAPTLMNAMAPK1L3MBTL1 | |
| Bicarbonate SCHEMBL7699565 | 0.72 | TDP1 (0.75) | TDP1MAPTLMNAMAPK1L3MBTL1 | |
| SCHEMBL28207503 | 0.72 | TDP1 (0.75) | TDP1MAPTLMNAMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |